The Binding of Isaac – Alternate Reality!
ISAAC CAN ONLY WISH THAT WAS TRUE
This is The Binding of Isaac: Rebirth
An awesome rogue-like indie game where you don’t get the cake and everything is terrible.
The game is full of poop, blood, mutated evil monsters and every time you get a powerup you become more messed up.
An example screenshot:
This is how you can look like after picking up a bunch of powerups.
Buy and play this game now!
Oh almost forgot, the end of my comic is referencing this screen in the game: